WebNov 17, 2024 · PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis. by Tim Wartewig, Zsuzsanna Kurgyis, Selina Keppler, Konstanze Pechloff, Erik Hameister, Rupert Öllinger, Roman Maresch, Thorsten Buch, Katja Steiger, Christof Winter, Roland Rad, Jürgen Ruland. Nature. Read more related scholarly scientific articles and abstracts. WebTim Wartewig's 11 research works with 291 citations and 1,144 reads, including: The fusion oncogene VAV1‐MYO1F triggers aberrant T‐cell receptor signalling in vivo and drives …

Tim Wartewig, MD-PhD - Physician-Scientist Postdoctoral

WebNov 26, 2024 · Psoriasis is a chronic inflammatory skin disease that affects 2 to 3% of the general population ().Debilitating skin lesions and associated systemic comorbidities severely impair patient quality of life ().Histopathologically, the scaling and itching skin of patients with psoriasis is characterized by hyperproliferative keratinocytes and mixed … WebTim WARTEWIG of Technische Universität München, München (TUM) Contact Tim WARTEWIG tiniest snowman

Peripheral T cell lymphoma: new model - Semantic Scholar

WebTim Wartewig 1 , Jürgen Ruland 2 Affiliations 1 Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany; … WebMay 10, 2010 · Tim Wartewig, Z. Kurgyis, +9 authors J. Ruland; Biology, Medicine. Nature. 2024; TLDR. It is shown that the acute enforcement of oncogenic TCR signalling in lymphocytes in a mouse model of human T cell lymphoma drives the strong expansion of these cells in vivo, but this response is short-lived and robustly counteracted by cell ... WebThe inhibitory receptor PD-1 is critical to balancing antigen-induced T cell activation; its inhibition is currently being explored to enhance antitumor T cell immunity with certain successful outcomes. However, PD-1 has also emerged as a central tumor suppressor in T cell lymphomas, where the tumor cell originates from a T cell itself. These aggressive … tiniest single board computer